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PMID: 32774757
Methods: 50 subjects from the Amazon region, diagnosed with gastritis that routinely used commercial (usual) water with a pH lower than 5.0, were enrolled to change the consume water to a pH of 8.5 to 10.0 for 5 months.
Results: Endoscopic findings of gastritis were such different (less severe disease), P = 0.024; in 43% diagnosed with moderate gastritis upfront esophagogastroduodenoscopy (EGD) presented mild gastritis after the consumption of alkaline water, according to study methods; there were no worsening gastritis and there were a significant increase in the expression of miR-135b (P = 0.039) and miR-29c (P = 0.039).
Conclusion: Modified pH range water (from 8.0 to 10.0) ingested for 5 months was able lead to a less severe gastritis according to the Sidney classification system, suggesting that this lifestyle change represented a clinical benefit in patients with gastritis on the Amazon region. In addition, higher expression of miR-135b and miR-29c was observed after the consumption of alkaline water for 5 months.
| Publish Year | 2020 |
|---|---|
| Country | Brazil |
| Rank | Positive |
| Journal | American Journal of Translational Research |
| Primary Topic | Stomach |
| Secondary Topic | Cancer |
| Model | Human |
| Tertiary Topic | Gastritis |
| Vehicle | Water (Electrolysis) |
| pH | Alkaline |
| Application | Ingestion |
| Comparison | Acidic Water |
| Complement |