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Studies Found: 1104

PREGNANCY - MILK PRODUCTION

Influences of alkaline ionized water on milk electrolyte concentrations in maternal rats

Year Published: 2001

We previously reported that body weight on day 14 after birth in male offspring of rats given alkaline ionized water (AKW) was significantly heavier than that in offspring of rats given tap water (TPW), but no significant difference was noted in milk yield and in suckled milk volume between the two groups. Additionally, the offspring in the AKW group and TPW group were given AKW and TPW, ...
WHOLE BODY - DIVING

On the Physiology of Hydrogen Diving and Its Implication for Hydrogen Biochemical Decompression

Year Published: 2000

Biochemical decompression, a novel approach for decreasing decompression sickness (DCS) risk by increasing the tissue washout rate of the inert gas, was tested in pigs during simulated H2 dives. Since there is only limited physiological data on the use of H2 as a diving gas, direct calorimetry and respirometry were used to determine whether physiological responses to hyperbaric H2 and He are ...
WHOLE BODY - DIVING

Changes in maximal performance of inspiratory and skeletal muscles during and after the 7.1-MPa ...

Year Published: 2000

During the 7.1-MPa hydrogen-helium-oxygen record human dive, we tested the hypothesis that the increased ambient pressure would alter the maximal muscle performance, specifically that breathing dense gas would lead to fatigue of the respiratory muscle. A group of hand muscles (adductor pollicis, AP) and the inspiratory muscles (IM) were studied in three professional divers. Maximal voluntary ...
SKIN - WOUND HEALING

Effectiveness of Electrolyzed Oxidized Water Irrigation in a Burn-Wound Infection Model

Year Published: 2000

The purpose of the study was to determine whether electrolyzed oxidized water (EOW) functions as a bactericide in burn injury with Pseudomonas aeruginosa infection in a rat burn-wound model. Anesthetized Sprague-Dawley rats (n = 31) were subjected to third-degree burns to 30% of total body surface area. Two days after injury, all rats were infected with P. aeruginosa using 1 mL of a suspension ...
SKIN - WOUND HEALING

Electrolyzed Strong Acid Aqueous Solution Irrigation Promotes Wound Healing in a Burn Wound Model

Year Published: 2000

The purpose of the study was to understand the effectiveness of electrolyzed strong acid aqueous solution (ESAAS) for acceleration of epithelialization in a rat burn wound model. Eighteen anesthetized Sprague-Dawley rats received 30% total body surface area third-degree burns, and 2 days after injury, the wound eschars were removed. Rats were divided into 3 groups: Group 1, no irrigation; Group 2, ...
HEART - SURGERY/TRANSPLANTATION

Treatment for Abdominal Aortic Graft Infection: Irrigation with Electrolyzed Strong Aqueous Acid, ...

Year Published: 2000

We report on successful surgical treatment of consecutive three patients with infection of an abdominal aortic graft, Therapy involved a combination of removal of the infected graft, elaborate debridement, irrigation with electrolyzed strongly acidic aqueous solution (ESAAS), in-situ regrafting, and omentoplasty. The use of ESAAS is discussed.
SKIN - WOUND HEALING

Effect of electrolyzed water on wound healing

Year Published: 2000

Electrolyzed water accelerated the healing of full-thickness cutaneous wounds in rats, but only anode chamber water (acid pH or neutralized) was effective. Hypochlorous acid (HOCl), also produced by electrolysis, was ineffective, suggesting that these types of electrolyzed water enhance wound healing by a mechanism unrelated to the well-known antibacterial action of HOCl. One possibility is that ...
MOUTH - DENTIN INTEGRITY

Bactericidal effect of electrolyzed neutral water on bacteria isolated from infected root canals

Year Published: 1999

The purposes of this study were to examine the time-related changes in pH, oxidation-reduction potential, and concentration of chlorine of electrolyzed neutral water and to evaluate the bactericidal effect of electrolyzed neutral water against bacteria from infected root canals. Various properties of electrolyzed neutral water--pH value, oxidation-reduction potential, and concentration of ...
PANCREAS - SURGERY/TRANSPLANTATION

Effectiveness of Acidic Oxidative Potential Water in Preventing Bacterial Infection in Islet ...

Year Published: 1999

At a number of points in the current procedures of islet isolation and islet culture after the harvesting of donor pancreata, microorganisms could potentially infect the islet preparation. Furthermore, the use of islets from multiple donors can compound the risks of contamination of individual recipients. Acidic oxidative potential water (also termed electrolyzed strong acid solution, function ...
WHOLE BODY - DIABETES (TYPE II)

Electrolyzed and Natural Reduced Water Exhibit Insulin-Like Activity on Glucose Uptake into Muscle ...

Year Published: 1999

In the type 2 diabetes, it has become clear that reactive oxygen species (ROS) cause reduction of glucose uptake by inhibiting the insulin-signaling pathway in muscle cells and adipocytes. We demonstrated that electrolyzed-reduced water (ERW) scavenges ROS and protects DNA from oxidative damage1). Here we found that ERW scavenges ROS in insulin-responsive L6 myotubes and mouse3T3/L1 adipocytes. ...
HEART - CARDIAC DEGENERATION

Histopathological influence of alkaline ionized water on myocardial muscle of mother rats

Year Published: 1999

We have reported that a marked necrosis and subsequent fibrosis of myocardium occurred among male rats 15 weeks old given alkaline ionized water (AKW) during gestation and suckling periods, and after weaning. In this study, it was examined whether similar lesions would occur in mother rats which were given AKW from day zero of gestation to day 20 of lactation. The myocardial lesion in the mother ...
PREGNANCY - MILK PRODUCTION

Influences of alkaline ionized water on milk yield, body weight of offspring and perinatal dam in ...

Year Published: 1999

The authors previously reported that male offspring of mothers rats given alkaline ionized water (AKW) showed a significantly higher body weight by day 14 after birth than did offspring of mother rats given tap water (TPW); furthermore, marked myocardial necrosis and fibrosis were observed particularly in the former male offspring at the age of 15 weeks. In the present experiment we looked for ...
WHOLE BODY - AGING

Effect of electrolyzed water intake on lifespan of autoimmune disease prone mice

Year Published: 1998

Recent studies on electrolyzed water indicate that anode or acidic water is most effective as disinfectants; whereas, reduced or alkaline water processed through cathode is used as safe drinking water. The present drinking water study was undertaken in two strains of autoimmune disease prone mice to establish the spontaneous disease process and longevity. Weanling MRL/lpr and NZBxNZW [B/W] F1 ...
WHOLE BODY - CANCER

Electrolyzed Reduced Water Which Can Scavenge Active Oxygen Species Supresses Cell Growth and ...

Year Published: 1998

Active oxygen species are considered to cause extensive oxidative damage to biological macromolecules, which bring about a variety of diseases as well as aging. Reduced water produced near cathode during electrolysis of water exhibits high pH, low dissolved oxygen, extremely high dissolvedmolecular hydrogen, and extremely negative redox potential values. Recently we found that strongly ...
HEART - CARDIAC DEGENERATION

Degradation of Myocardiac Myosin and Creatine Kinase in Rats Given Alkaline Ionized Water

Year Published: 1998

Recently, the authors have shown that marked necrosis and fibrosis of myocardium were observed in rats given alkaline ionized water (AKW). To clarify the cause of myocardial lesions, the activities of myosin ATPase, actomyosin ATPase and creatine kinase (CK) in myocardium of rats given AKW at 15 weeks-old were compared with those in myocardium of rats given tap water (TPW). Furthermore, sodium ...
WHOLE BODY - ROS-SCAVENGING

Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage

Year Published: 1997

Active oxygen species or free radicals are considered to cause extensive oxidative damage to biological macromolecules, which brings about a variety of diseases as well as aging. The ideal scavenger for active oxygen should be 'active hydrogen'. 'Active hydrogen' can be produced in reduced water near the cathode during electrolysis of water. Reduced water exhibits high pH, low dissolved oxygen ...
WHOLE BODY - SURGERY/TRANSPLANTATION

Successful Treatment of Mediastinitis after Cardiovascular Surgery Using Electrolyzed Strong Acid ...

Year Published: 1997

Dilute povidone-iodine solution has been widely used as an irrigant for the treatment of mediastinitis. However, its use is not without adverse effects and often cause? poor growth of pinulation tissues. To avoid the problems seen with the use of povidone-iodine solution, we applied electrolyzed strong acid aqueous solution (ESAAS) to mediastinal irrigation in 4 patients (2 infants and 2 adults) ...
PERITONIUM - SEPSIS

Trial of Electrolyzed Strong Acid Aqueous Solution Lavage in the Treatment of Peritonitis and ...

Year Published: 1997

Electrolyzed strong acid aqueous solution is acidic water that contains active oxygen and active chlorine and possesses a redox potential. We performed peritoneal and abscess lavages with an electrolyzed strong acid aqueous solution to treat 7 patients with peritonitis and intraperitoneal abscesses, who were seen in our department between December 1994 and April 1995. The underlying disease was ...
WHOLE BODY - DIVING

Decompression comparison of helium and hydrogen in rats

Year Published: 1997

The hypothesis that there are differences in decompression risk between He and H2 was examined in 1,607 unanesthetized male albino rats subjected to dives on 2% O2-balance He or 2% O2-balance H2 (depths < or = 50 ATA, bottom times < or = 60 min). The animals were decompressed to 10.8 ATA with profiles varying from rapid to slow, with up to four decompression stops of up to 60 min each. Maximum ...
SKIN - WOUND HEALING

Treatment of Infectious Skin Defects or Ulcers with Electrolyzed Strong Acid Aqueous Solution

Year Published: 1997

A chronic ulcer with an infection such as methicillin-resistant Staphylococcus aureus is hard to heal. Plastic and reconstructive surgeons often encounter such chronic ulcers that are resistant to surgical or various conservative treatments. We applied conservative treatment using an electrolyzed strong acid aqueous solution and obtained satisfactory results. The lesion was washed with the ...
HEART - CARDIAC DEGENERATION

INFLUENCE OF ALKALINE IONIZED WATER ON RAT ERYTHROCYTE HEXOKINASE ACTIVITY AND MYOCARDIUM

Year Published: 1997

Alkaline ionized water (AKW) produced by the electrolysis of tap water (TPW) was given to pregnant rats throughout gestation. AKW was subsequently given to infants as a test group until 15 weeks old to determine changes in body and organ weights, erythrocyte hexokinase (HK) activity and histological preparations of myocardiac muscle. The results were compared with those for rats given TPW. Body ...
WHOLE BODY - DIVING

ECG changes during the experimental human dive HYDRA 10 (71 atm/7,200 kPa)

Year Published: 1995

Electrocardiogram (ECG) analysis was performed in three human divers during a 71 atm (7,200 kPa) saturation dive (COMEX HYDRA 10 experiment). The inhaled gas mixture was slightly hyperoxic; its composition was basically helium and oxygen. Hydrogen was introduced during compression and its partial pressure reached 20 atm. ECG changes were the same in the three divers. Marked bradycardia rapidly ...
PREGNANCY - OFFSPRING DEVELOPMENT

Effect of alkaline ionized water on reproduction in gestational and lactational rats

Year Published: 1995

Alkaline ionized water (AKW) produced by electrolysis was given to gestational and lactational rats, and its effect on dams, growth of fetuses and offsprings were investigated. The results showed that the intake of food and water in dams increased significantly when AKW was given from the latter half of the gestation period and from the former half of the lactation period. Body weight of the ...
WHOLE BODY - DIVING

Psychophysiological reactions in humans during an open sea dive to 500 m with a ...

Year Published: 1994

Six commercial divers were investigated for neurological and psychosensorimotor responses during an open sea dive to 500 m with a hydrogen-helium-oxygen mixture containing 49% hydrogen. Results showed only moderate neurological symptoms of high-pressure nervous syndrome, whereas the narcotic effect of hydrogen was detectable, as investigated by psychosensorimotor tests. Nevertheless, the divers ...
INTESTINE - HYDROGEN BIOLOGY

Production, metabolism, and excretion of hydrogen in the large intestine

Year Published: 1992

Hydrogen is produced during fermentation in the large intestine and may be excreted in breath and flatus or further metabolized by the flora. However, there is little information about total H2 excretion from different substrates or the extent to which it is metabolized in the colon. We have therefore measured total H2 and methane excretion in 10 healthy subjects using a whole body calorimeter. ...