Suppressive effect of electrolyzed reduced water on the paraben-induced DNA damage in human dermal fibroblast cells
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DOI:
10.5762/KAIS.2010.11.11.4427
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Abstract:
Parabens have been widely used as preservatives in cosmetics due to the presumed low toxicity and long history of safe use. However, recent studies have shown the potent toxicity of parabens. In order to know if electrolyzed reduced water could suppress the oxidative DNA damage of HDF cell by methylparaben, one of the frequently used parabens, we performed comet assay in this study. As a result, interestingly, electrolyzed reduced water could suppress methylparaben-induced oxidative DNA damage in HDF cells.| Publish Year | 2010 |
|---|---|
| Country | South Korea |
| Rank | Positive |
| Journal | Journal of the Korea Academia-Industrial Cooperation Society |
| Primary Topic | Skin |
| Secondary Topic | Environmental Pollution |
| Model | Cell Culture |
| Tertiary Topic | Paraben Toxicity |
| Vehicle | Water (Electrolysis) |
| pH | Alkaline |
| Application | Culture Media |
| Comparison | |
| Complement |