Suppressive effect of electrolyzed reduced water on the paraben-induced DNA damage in human dermal fibroblast cells

A Yu, Kun Ryoo, Mi Lee

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DOI: 10.5762/KAIS.2010.11.11.4427 DOI is the universal ID for this study.

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Parabens have been widely used as preservatives in cosmetics due to the presumed low toxicity and long history of safe use. However, recent studies have shown the potent toxicity of parabens. In order to know if electrolyzed reduced water could suppress the oxidative DNA damage of HDF cell by methylparaben, one of the frequently used parabens, we performed comet assay in this study. As a result, interestingly, electrolyzed reduced water could suppress methylparaben-induced oxidative DNA damage in HDF cells.

Publish Year 2010
Country Korea
Rank Positive
Journal Journal of the Korea Academia-Industrial Cooperation Society
Primary Topic Skin
Secondary Topic Environmental Pollution
Model Cell Culture
Tertiary Topic Paraben Toxicity
Vehicle Water (Electrolysis)
pH Alkaline
Application Culture Media