Hydrogen Water Reduces Oxidative Stress in Healthy Adults
- Authors
- Kei Mizuno, Kyosuke Watanabe, Emi Yamano, Kyoko Ebisu, Kanako Tajima, Junzo Nojima, Yusuke Ohsaki, Shigeru Kabayama, Yasuyoshi Watanabe
- Journal
- Heliyon
- Year
- 2022
- DOI
- 10.1016/j.heliyon.2022.e11853
- Study Type
- Human
- Outcome
- Positive
- Peer Reviewed
- Yes
- Country
- Japan
- Health Condition
- Oxidative Stress
- Body System
- Whole Body
TL;DR
Drinking electrolyzed hydrogen water (EHW) every day may help reduce harmful oxidative stress in healthy adults, potentially lowering the risk of various diseases.
Key Finding
People who regularly drank electrolyzed hydrogen water had significantly lower levels of oxidative stress markers compared to those who didn't drink it.
Summary
This study looked at whether drinking electrolyzed hydrogen water (water treated with electricity to add hydrogen) every day could reduce oxidative stress in healthy people. Researchers compared 64 people who drank more than 500 mL of this water at least 5 days a week for at least 6 months to 470 people who didn't drink it. They found that the hydrogen water drinkers had lower levels of harmful oxidative compounds (molecules that damage cells) and better antioxidant markers than the control group.
Practical Takeaway
This observational study suggests that daily hydrogen water consumption may support antioxidant activity in healthy adults, though the study design (comparing existing habits rather than randomly assigning people to drink it) limits how strongly we can conclude this. The findings are preliminary and would benefit from larger, controlled trials to confirm whether hydrogen water actually causes these changes or if other factors explain the differences between groups.
Abstract
Chronic oxidative stress induces deterioration of health and a risk for the onset of various diseases. Previous clinical studies revealed that electrolyzed hydrogen water (EHW) is effective to reduce oxidative stress during hemodialysis in patients with chronic dialysis. In the present observational study, we investigated the antioxidant effects of a daily continuous intake of EHW in healthy adults. The concentrations of serum reactive oxygen metabolites-derived compounds (d-ROMs) and blood urea nitrogen in healthy volunteers (n = 64) who had a habit of intake over 500 mL/day of EHW at least 5 days a week for longer than 6 months were lower than those of age- and sex-matched controls (n = 470) without the habit of EHW intake. Oxidation stress index which the ratio between concentrations in d-ROMs and biological antioxidant potential was correlated with the serum concentration of high-sensitivity C-reactive protein or low-density lipoprotein cholesterol in the EHW group. These results suggest that the continuous intake of EHW induces antioxidant effects and may contribute to alleviate the risk of various oxidative stress-related dysfunctions and diseases in healthy adults.